This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Watermelon is a nutrient-rich fruit that has many health benefits. For example, watermelon is the perfect bedtime snack because its low in calories and high in water content. Fibre helps add bulk to stool, and it also regulates bowel movements. The entire list of reference links is also provided at the bottom of the article. WebBitter Melons. J Ethnopharmacol 2004;91(2-3):257-262. Quantity/Pack: 2 Pounds. Citrulline is converted to arginine in the body, which is involved in nitric oxide production. This study analyzed the hypoglycemic effects of bitter melon extract and seeds on mice with either normal or elevated blood sugar levels. The antioxidant and anti-inflammatory properties of turmeric, mainly due to its compound curcumin, is responsible for weight loss. This fruit has a very warty, ridged exterior and is harvested before ripening, as it becomes increasingly bitter. Health benefits of apple cider vinegar include its ability toregulate blood sugar levels, boost weight loss,improve skin & gut health, & lower cholesterol levels.Read more! He co-founded the literary journal, Sheriff Nottingham, and now serves as the Content Director for Staind Arts, a non-profit based in Denver, Colorado. WebMD does not provide medical advice, diagnosis or treatment. Bourinbaiar AS, Lee-Huang S. The activity of plant-derived antiretroviral proteins MAP30 and GAP31 against herpes simplex virus in vitro. T. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: s systematic review and meta-analysis. Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats. If youre already prone to these things, bitters aggravate them by making your digestive tract a little bit more reactive, Czerwony cautions. This is a very powerful fruit, and it is highly recommended that you speak with your doctor or physician before adding it to your diet. Watermelons are a diuretic food, meaning they promote urination. Cramping. Biochem J 1993;292:267-70. Due to its antibacterial properties, traditionally (and sometimes still today) bitter melon has also beenused topically on the skin to treat deep skin infections (abscesses) and wounds without the use of antibiotics. 2000;9(1):138-144. You can always eat more if you feel OK. No, eating watermelon before bed does not make you fat. These data suggest that a peripheral antifatigue effect of bitter melon is mediated by ammonia and not uric acid metabolism. They began cooking and using the fruit in recipes, as well as juicing it to create a tonic in order to help treat such conditions as indigestion, an upset stomach, skin wounds, chronic coughs and respiratory infections. Pomelos are rich in vitamin C & potassium among other nutrients & antioxidants. If you are prone to diarrhoea, you may want to avoid eating watermelon before bed. Disclaimer: You must always consult your doctor before including a new supplement or food into your daily routine as only your doctor can explain any pros or cons that are specific to you. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. WebHealthline: Medical information and health advice you can trust. Select a condition to view a list of vitamins. Protein Sci. Dans AM, Villarruz MV, Jimeno CA, et al. View abstract. Pros Of Eating Watermelon Before Bed 1. The pros and cons of eating watermelon before bed depend on your situation. View abstract. AIDS Asia 1995;2(4):6-7. Its best known for its hypoglycemic affects (the ability to lower blood sugar), and research shows that themelons juice, fruit and dried powder can all be used to mimic insulins effects and treat diabetes. Stepka W, Wilson KE, and Madge GE. Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31. Some people can eat a large piece of watermelon before bed without any problems, while others may experience stomach upset or diarrhoea if they overeat. (Gupta 2017, Hui 2009, Tongia 2004), Individuals with diabetes should be advised to closely monitor blood sugar if adding bitter melon to their treatment regimen. Bitter melon has been the focus of well over 100 clinical and observational studies. Medicine (Baltimore) 2021;100(27):e26606. Based on research thats available at this time, bitter melon is meant to be used in conjunction with other preventive measures (like eating a healthy diet and exercising to control inflammation), along with conventional treatments when necessary. View abstract. In one report of a child given the juice, vomiting, diarrhea, and eventual death occurred.Duke 1989. This information should not be used to decide whether or not to take this product. Minor effects on cytochrome P450 enzymes and glutathione S-transferase were observed in one experiment. If you are healthy and do not have any allergies or digestive issues, watermelon can be an excellent food to eat before bed. Commonly found used in East/Southeast/South Asian cuisine with origins in Africa. However, the pith becomes sweet and is deep red in color.Chevallier 1996, Tcheghebe 2016, USDA 2017, The unripe fruit is commonly consumed as a vegetable and is a culinary fruit in Asia. Bitter melon is a plant. Cell Immunol 1990;126:278-89. View abstract. Its bedtime and you see that tasty looking watermelon on the kitchen table. The sweet taste and refreshing texture will help you relax and prepare for a good nights sleep. 1986;15(1):107-117. Watermelon is a high-acid fruit that can cause heartburn in some people. (Boetse 2011, Coutinho 2010, Hsu 2012, Li 2012, Raina 2016, Ray 2010, Waiyaput 2012, Weng 2013), The hypoglycemic effects of bitter melon have been established in animal studies. (. Interaction between curry ingredient (karela) and drug (chlorpropamide). Its most well-known benefits are theabilityto help manage diabetes, reduce the effects of hemorrhoids, improve respiratory health, and boostskin health. So, eating watermelon before bed can help you fall asleep by increasing your bodys production of this sleep-inducing hormone. Eating it before bed may cause discomfort and make it difficult to sleep if you are allergic to watermelon. While bitter melon did lower blood glucose levels, it didnt have as much of an effect as the metformin did. Eating watermelon before bed may cause you to wake up more at night to use the restroom. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Although consumption of M. charantia extract (100 mL/dose) 6 times/day significantly increased ammonia levels "before," "during," and "immediately after" exercise relative to ammonia increases observed before supplementation, levels measured the "morning after exercise" dropped significantly (P<0.05) with supplementation and were even lower than presupplementation values (79.5 vs 90.45 mcg/dL, non-significant difference); no significant effect of M. charantia extract was observed on uric acid levels. Benefits include increasing immunity, lowering diabetes symptoms, fighting free radical damage and inflammation, treating skin problems, improving digestion and helping to prevent cancer. Marketable fruit is produced 15-20 days after fruit set.1-3 Bitter melon grows well in hot and humid areas with well drained sandy loam soils. There is no scientific evidence to support this claim, but the sugar content in watermelon may cause some people to have vivid dreams. Diabetes: Bitter melon juice has been administered for type 2 diabetes at daily doses of 50 to 100 mL; 5 g of dried fruit given 3 times/day has also been used. The well-studied benefits are listed below: According to a 2005 study, bitter melon is one of the most potent fruits for managing diabetes mellitus. Drinking water or eating watermelon before bed can help prevent this from happening. Watermelons may contain compounds that can act as allergens for some people. 1983;7(2):169-173. Fertil Steril 1999;72:686-90. WebBitter melon ( Momordica charantia) is a tropical relative of the cucumber. View abstract. Some of the risks and complications of bitter melon include: diarrhea, vomiting, and View abstract. Research has demonstrated that bitter melon contains several forms of antibacterial as well as antiviral agents. 2018;32:181-6. doi: 10.1016/j.ctcp.2018.06.012. Bitter melon is a member of the Cucurbitaceae family. The LWT Food Science and Technology journal has covered a study suggesting that bitter melon is a source of many different antioxidants that make ita powerful [7]defense against illnesses in the body. Br J Pharmacol. View abstract. Yue J, Sun Y, Xu J, et al. Br Med J (Clin Res Ed) 1981;282:1823-4. The fruit has been used to treat asthma, colic, constipation, cough, gout, helminthiases, inflammation, leprosy, and ulcers. J Med Assoc Thai. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. muricata),mostly throughout parts of India. This information is not specific medical advice and does not replace information you receive from your health care provider. In addition, eating watermelon before bed may lead to uncomfortable digestive symptoms like bloating, gas, and diarrhoea. The Foods You Should Avoid With Insomnia: Tips & How To Sleep Better, Why Does Water Taste Better At Night? (Choudhary 2012, Huang 2013, Leung 2009, Wang 2017), While bitter melon has traditionally been used for treatment of type 2 diabetes, medical literature documents inconsistent results and poor methodology among clinical trials evaluating its effects in diabetes. This can be a stimulant for some people and may make it difficult to fall asleep. Cover the hole with topsoil. Eating watermelon at night has potential benefits and drawbacks that you should be aware of. (Kwak 2020), Crude lectin extracted or isolated from M. charantia seed upregulated immune response in vitro,(Huang 2008, Huang 2008) while a pulp extract increased the production of hepatocyte growth factor. These agents are capable of lowering susceptibility to such infections as Helicobacter pylori (a very common bacteria tied to the formation of stomach ulcers when someones immune function is low), along with viruses including HIV. Effect of Momordica charantia administration on anthropometric measures and metabolic profile in patients with obesity: a pilot clinical trial. (1). It began to spread more than 600 years ago. 5 Reasons to Add Lamb Meat to Your Diet, St. Johns Wort Benefits for Depression, PMS & Menopause, Reducing respiratory infections such aspneumonia, Lowering inflammation and raising immunity, Treating abdominal pain, peptic ulcers, constipation, cramps and fluid retention, Treating skin conditions including eczema, scabies andpsoriasis, Antiviral,antibacterial and anthelmintic properties (including those that can be used to prevent or treat parasites, HIV/AIDS, malaria and even leprosy), Managing symptoms of autoimmune disorders including rheumatoid arthritis. In the Northern Hemisphere, the plant produces yellow flowers during June and July, and produces fruit September through November. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Lee-Huang S, Huang PL, Chen HC, et al. Lee-Huang S, Huang PL, Nara PL, et al. View abstract. Medical literature documents numerous studies of bitter melon use, primarily for its antidiabetic activity, but results are conflicting and inconclusive. Extracts of various parts of bitter melon are used in traditional African medicine. Watermelons are a high-sugar fruit that can contribute to weight gain if overeaten. This information may not fit your specific health circumstances. Bitter melon plants put on growth rapidly, so no more than one seed should be sown in each pot to allow adequate room for the roots to spread. 2005 - 2023 WebMD LLC. There is insufficient clinical evidence to substantiate these doses. Melatonin is a hormone that helps regulate your natural sleep cycle. If you have a medical issue or concern you must always see your doctor and ask them for advice. Planta Med 1990;56:426-9. However, once in a while, it is acceptable to eat it before bed. Bitter melon generally causes few adverse reactions. GI effects (eg, abdominal pain, diarrhea) and headache have been reported. Case reports of hypoglycemic coma and atrial fibrillation associated with bitter melon intake exist. Bitter melon should be used with caution in patients with impaired hepatic function. 2020 Aug;52:102524. doi: 10.1016/j.ctim.2020.102524. WebHeat a wok over medium-high heat and add 2 tablespoons of peanut oil. Read more! Doctors don't know if its safe to take it for longer periods. Long-term safety has Ali L, Khan AK, Mamun MI, et al. View abstract. In Guyana traditional medicine, a leaf extract tea has been used in diabetes and as an antiviral. In many ways, bitter melon extract acts just like insulin that the body produces naturally. Its fruit is cucumber-shaped with surface bumps. It is most commonly found in Africa, Asia, and the Caribbean. The antimicrobial and antioxidant properties of the gourd help in purification of the blood, thereby promoting skincare. Bitter melon, also known as bitter gourd, bitter cucumber or karela, is a gourd-like plant widely cultivated in Asia, India, Africa and South America. Cancer Res 1983;43:5151-5. The benefits of the fruit are found in its flesh, which has the consistency of cucumber or green pepper before itripens. Phytother Res 1993;7:285-9. 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