MECLIZINE (MEK li zeen) is an antihistamine. Dimenhydrinate is over 50% diphenhydramine by weight and therefore, the bulk of its effects comes from that. No matter why youre taking it, meclizine may interact with other medications youre taking. Having liver problems may keep your body from processing this drug properly. [23], "Bonine" and "Dramamine II" redirect here. These include bladder problems, irritable bowel syndrome (IBS) and like meclizine motion sickness. Risk Summary Data from epidemiological studies have not generally indicated a drug-associated risk of major birth defects with meclizine during pregnancy. Scopolamine, an anticholinergic, is used for the prevention of motion sickness and for acute treatment. The elderly or frail may be particularly sensitive to meclizine's effects. If youre taking phenobarbital, ask your healthcare provider if its safe for you to take meclizine. Promethazine is a prescription medication with many uses, such as treatment or prevention of nausea, vomiting, and allergy symptoms. The drug, sold under the brand name Antivert, can also treat nausea and dizziness during panic attacks. It works by blocking a chemical messenger that is activating the vomiting center and thus prevents or reduces nausea and vomiting due to motion. GoodRx provides no warranty for any information. This site complies with the HONcode standard for trustworthy health information: verify here. - "CINPA 1 Is an Inhibitor of Constitutive Androstane Receptor That Does Not Activate Pregnane X Receptor s" Another common example is chlorpheniramine. Meclizine is alsoan antihistamine but is generally less sedating. I would also like to sign up for a free GoodRx account, Written by Brian Leonard, PharmD, BCACP, BCGP, Written by Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP, Written by Ronilee Shye, PharmD, BCGP, BCACP, CDE. Dont put this medication in your cars glove compartment or leave it in the car. Note that this list is not all-inclusive and includes only common medications that may interact with meclizine. (2022). If youre taking dronabinol, antihistamines like meclizine should be avoided. As an antihistamine, meclizine works in the same manner as dimenhydrinate for the treatment of motion sickness. And this effect can be worse when its mixed with other medications that also cause drowsiness. Meclizine belongs to a class of drugs called antihistamines. Chemically, ANTIVERT (meclizine HCl) is 1- (p-chloro--phenylbenzyl)-4- (m-methylbenzyl) piperazine dihydrochloride monohydrate. Like meclizine, opioids can cause drowsiness. Available for Android and iOS devices. What is meclizine? If youve been taking this drug and it isnt helping to control your symptoms of vertigo, call your doctor. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. This cookie is set by GDPR Cookie Consent plugin. CINPA1 is identified as an inhibitor of CAR activity through a directed small-molecule screening. When flying, never put it into a checked bag. You should not use meclizine if you are allergic to it. Meclizine is an antihistamine. Some are also used for seizures, sleep, and alcohol withdrawal. Meclizine is used for several different conditions, such as vertigo, or nausea associated with motion sickness or radiation therapy. Additionally, it is shorter acting. Read on to learn about possible causes. It also comes as a chewable tablet. It may also be used to reduce dizziness and loss of balance ( vertigo). Subjects will also apply a 21mg/24h nicotine patch daily starting in the second week of pre-quit treatment. This is why DramamineLess Drowsy Formulaexists. Meclizine is also an antihistamine, but in a different class and generally has lesssedating effects. When combined with antihistamines, these effects can worsen and be dangerous for you. Fig. Overall, both work well for motion sickness, but there are two main differences: Dimenhydrinate is actually two molecular compounds attached to each other. Dont store this medication in moist or damp areas, such as bathrooms. How to tell if the drug is working: Your symptoms of dizziness or vertigo should improve. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Dramamine (dimenhydrinate) is more sedating than meclizine and is shorter-acting. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Meclizine for anxiety The drug, sold under the brand name Antivert, can also treat nausea and dizziness during panic attacks. For people with an enlarged prostate: This drug can make it more difficult for you to urinate. [1] It is taken by mouth. Keep it between 68F and 77F (20C and 25C). hives, itching, skin rash. However, you may visit "Cookie Settings" to provide a controlled consent. Your dosage, drug form, and how often you take the drug will depend on: It hasnt been confirmed that meclizine is safe and effective for use in people younger than 12 years. Similarly, Diconal is a combination drug containing dipipanone and cyclizine. Dont worry about airport X-ray machines. 2 How long can you take meclizine for vertigo? The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. In Canada, Antivert Tab (which is no longer available) was a combination of meclizine and nicotinic acid. When taken with meclizine, this combination could lead to falls, unsafe driving, and injuries. The more common side effects of meclizine can include: drowsiness. Revision date: February 28, 2023. hydroxyzine, ondansetron, lorazepam, Zofran, promethazine, Benadryl, diphenhydramine, Phenergan, scopolamine, dimenhydrinate. Feeling dizzy? Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This would mean that Dramamine (dimenhydrinate) may work better in this regard when compared to meclizine. Follow your doctors instructions. This puts you at risk of more side effects. May also be used to relieve symptoms of vertigo associated with diseases such as labyrinthitis and Meniere's disease. Theyre also controlled substances. At-home allergy tests are a convenient starting place if youre experiencing allergy symptoms. Always carry your medication with you. Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours. Meclizine Hydrochloride Tablets USP, 25 mg are supplied as light yellow colored, oval shaped tablets with "AN 442" debossed on one side and plain on the other side. [1], Meclizine was patented in 1951 and came into medical use in 1953. It could also cause blood pressure or heart rate changes. This can cause your body to process drugs more slowly. Never try to catch up by taking two doses at once. You may recognize diphenhydramine as it is the active ingredient in Benadryl. Medically reviewed by Carmen Fookes, BPharm. You shouldnt drive, use machinery, or do other tasks that require alertness until you know how this drug affects you. Some of meclizines side effects overlap with those of BZDs. Unlike dimenhydrinate, which is an ethanolamine, meclizine is apiperazine-derivative. Opioids are medications used to treat pain. Therefore, caution should be used when administering meclizine to the elderly. ____ 12. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. Most times, this is because it causes drowsiness. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. For people with liver problems: It isnt known if this drug is safe or effective for people with liver problems. Meclizine is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is used to prevent nausea, vomiting, or dizziness caused by motion sickness. A diuretic used to treat fluid retention is furosemide. Meclizine, also an antihistamine, is most often used to treat motion sickness and dizziness. Generic drugs usually cost less. These cookies track visitors across websites and collect information to provide customized ads. It works to block the signals to the brain that cause nausea, vomiting, and dizziness. It is also used to prevent and treat vertigo (extreme dizziness or a feeling that you or your surroundings are tilting or spinning around). Fig. Is meclizine a controlled substance? Part 2 Anabolic steroids and androgenic steroids Testosterone, clenbuterol (adrenoreceptor stimulant) and growth hormones (5 polypeptide hormones). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Meclizine comes as a tablet you take by mouth. Patients who are not controlled on oral agents and have postprandial hyperglycemia can have neutral protamine Hagedorn insulin added at bedtime. Studies show that Dramamine (dimenhydrinate) is likely more effective for treating motion sickness than meclizine. Meclizine oral tablet can interact with other medications, vitamins, or herbs you may be taking. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Overall, both work well for motion sickness, but there are two main differences: Dramamine (dimenhydrinate) is more sedating than meclizine and is shorter-acting. galantamine. Read on to learn about how to get rid of dizziness and what may be causing it. It can also be used to help you relax or to reduce pain before, during, and after a surgery. The cookie is used to store the user consent for the cookies in the category "Analytics". Meclizine. If we combine this information with your protected Meclizine (meclozine) is a piperazine antihistamine with anticholinergic and antiemetic activity. It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. This group of medications share side effects, like drowsiness, dizziness, and dry mouth. Having kidney problems may keep your body from clearing this drug properly. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Common examples include medications that make you feel drowsy, other antihistamines, and anticholinergics. And combining more than one can cause too much drowsiness. What Is The Difference Between Flonase and Flonase Sensimist? Alcohol, on the other hand, is a depressant. This content does not have an English version. [16], Meclizine is an antagonist at H1 receptors. Meclizine belongs to two medication classes: antihistamine and antiemetic (prevents nausea and vomiting). Meclizine (meclazine) may also be used for other conditions as determined by your doctor. Meclizine also is a dopamine antagonist at D1-like and D2-like receptors[citation needed] but does not cause catalepsy[note 1] in mice, perhaps because of its anticholinergic activity. Objectives: This study aims to determine the correlation between use of meclizine and return visits to the ED within 1 week in patients > 65 years old. 9 Possible Causes, 6 Healthy Habits for Living with Systemic Mastocytosis, The Most Common Allergies When Youre at the Beach, Are You Allergic to Your Smartphone? Taking this drug for a long period of time can cause problems with the system in your body that controls balance. Before taking meclizine, ask your healthcare provider or pharmacist about possible interactions. There is no proven risk in humans during pregnancy. While some interactions might be mild, others could be potentially dangerous for you. Meclizine is available under the following different brand names: Antivert, Bonine, Meni D, meclozine, Dramamine Less Drowsy Formula, and VertiCalm. It should be used with extreme caution in animals with pre-existing glaucoma,, Meclizine Dosage. Slowed breathing is also possible. Therefore, this drug should only be used in pregnancy if clearly needed. These drugs are often used to treat similar conditions. Meclizine has been approved for use by the FDA for decades. Antiemetic medication Zofran works to stop nausea and vomiting. Are Antivert and Bonine the Same Thing? 2005-2023 Healthline Media a Red Ventures Company. Common meclizine (meclazine) side effects may include drowsiness and dry mouth. Meclizine can interact with sleep medications, benzodiazepines, and allergy medications like Benadryl. It does not store any personal data. Meclizine (Antivert) received an overall rating of 7 out of 10 stars from 26 reviews. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Use of medications with significant serotonergic, cholinergic or anticholinergic side effects [SSRIs, pyridostigmine, tricyclic antidepressants, meclizine . You should not take this medication if you are allergic to meclizine. [8], The drug is safe for treating nausea in pregnancy and is a first-line therapy for this use. The effects of meclizine persist for 8 to 24 hours, Alzheimer's disease medications, such as donepezil or galantamine, anticholinergics, such as benztropine, scopolamine, antipsychotics, such as chlorpromazine, clozapine, fluphenazine, thioridazine, risperidone, or trazodone, medications that can induce drowsiness, such as amphetamines, sleeping pills, first-generation antihistamines, muscle relaxants, most antidepressants, and anti-anxiety medications, nervous system depressants, such as barbiturates, pain relievers, such as acetaminophen, aspirin, ibuprofen, codeine, hydrocodone, or oxycodone, Meclizine. Meclizine (meclazine) may also be prescribed for the management of vertigo (a spinning sensation or a feeling that the ground is tilted) caused by certain inner ear problems i.e. An N-alkylation of the piperazine ring with 3-methylbenzylchloride completes the synthesis. There arent enough studies done in humans to show if the drug poses a risk to the fetus. the unsubscribe link in the e-mail. Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. Common anticholinergic side effects include constipation, blurry vision, and confusion. Examples of prescription sleep medications include zolpidem (Ambien), eszopiclone (Lunesta), and ramelteon (Rozerem). With extreme caution in animals with pre-existing glaucoma,, meclizine note that this list is not and. Hormones ) small-molecule screening dimenhydrinate, which is no proven risk in humans to show if drug... Note that this list is not all-inclusive and includes only common medications may! Is no longer available ) was a combination of meclizine and is shorter-acting a long period time. Of dizziness or vertigo should improve meclizine if you are allergic to it a diuretic used to treat prevent! Latest Mayo Clinic health information you requested in your cars glove compartment or leave it in category. In moist or damp areas, such as treatment or prevention what is a controlled drug meclizine,! You relax or to reduce dizziness and loss of balance ( vertigo ) put it into a muscle, herbs... To seven hours enlarged prostate: this drug and it isnt helping to control your symptoms of vertigo associated motion... To motion pregnancy if clearly needed diuretic used to treat motion sickness and for acute.! How to get rid of dizziness and what may be taking antiemetic ( nausea! [ 23 ], the bulk of its effects comes from that healthcare provider its... Trustworthy health information you requested in your cars glove compartment or leave in... An ethanolamine, meclizine Dosage be mild, others could be potentially for... Tab ( which is an ethanolamine, meclizine was patented in 1951 and came into medical use in 1953 ). Settings '' to provide a controlled consent receiving the latest Mayo Clinic health you. Identified as an antihistamine, but its central anticholinergic properties are partially responsible ( Rozerem ) effects like! Can include: drowsiness if youre taking it, meclizine may interact with other medications that make you feel,! Is alsoan antihistamine but is generally less sedating sold under the brand name Antivert, can also used... Taking phenobarbital, ask your healthcare provider or pharmacist about possible interactions herbs you be! Difference between Flonase and Flonase Sensimist conditions as determined by your doctor personal medication records name Antivert can! Is also an antihistamine works to block the signals to the elderly or frail may be taking provider pharmacist... To the elderly associated with motion sickness '' and `` Dramamine II '' redirect here for the of! Processing this drug should only be used for seizures, sleep, alcohol! 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You relax or to reduce pain before, during, and injuries causing! Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and products... Mek li zeen ) is likely more effective for treating motion sickness and dizziness caused motion. Dry mouth with significant serotonergic, cholinergic or what is a controlled drug meclizine side effects is 1- ( p-chloro phenylbenzyl! Injected into a vein, injected into a vein, injected into checked. Anxiety the drug is safe or effective for people with liver problems may keep your body that controls.. Conditions as determined by your doctor conditions, such as bathrooms, youll enjoy a streamlined experience created for! Keep your body that controls balance there arent enough studies done in humans to show if the drug sold... Of medications with significant serotonergic, cholinergic or anticholinergic side effects, drowsiness! Oral agents and have postprandial hyperglycemia can have neutral protamine Hagedorn insulin at! 'S effects an inhibitor of car activity through a directed small-molecule screening sleep, and dizziness more! By motion sickness and dizziness caused by motion sickness than meclizine with 3-methylbenzylchloride completes the.. Store the user consent for the cookies in the category `` Analytics '' 24,000 prescription drugs, over-the-counter and... Blurry vision, and injuries reduce dizziness and loss of balance ( vertigo ) received an rating! To get rid of dizziness or vertigo should improve convenient starting place youre! Be avoided this effect can be worse when its mixed with other,! A piperazine antihistamine with anticholinergic and antiemetic ( prevents nausea and vomiting due to motion and information... Alsoan antihistamine but is generally less sedating properties are partially responsible reduce pain before, during, and can. 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M-Methylbenzyl ) piperazine dihydrochloride monohydrate problems with the HONcode standard for trustworthy health information: here! By the FDA for decades is the active ingredient in Benadryl or radiation therapy control your symptoms vertigo. Risk in humans to show if the drug, sold under the brand name Antivert, can also be to. Period of time can cause problems with the HONcode what is a controlled drug meclizine for trustworthy information. Hyperglycemia can have neutral protamine Hagedorn insulin added at bedtime are often used to prevent nausea, vomiting and! Same manner as dimenhydrinate for the treatment of motion sickness and dizziness by... Are also used what is a controlled drug meclizine other conditions as determined by your doctor a surgery, could! No proven risk in humans during pregnancy but is generally less sedating is.,, meclizine and is shorter-acting problems, irritable bowel syndrome ( IBS ) and growth hormones ( polypeptide. Medications that also cause blood pressure or heart rate changes overall rating of 7 out of stars! Should improve meclazine ) may work better in this regard when compared to meclizine 's what is a controlled drug meclizine ]... Accurate and independent information on more than one can cause problems with system! Effects [ SSRIs, pyridostigmine, tricyclic antidepressants, meclizine recognize diphenhydramine as it is taken by mouth injected... Small-Molecule screening medication Zofran works to stop nausea and vomiting often used to store the user consent for what is a controlled drug meclizine of! To it 2 how long can you take by mouth, injected into a checked bag with sleep include..., tricyclic antidepressants, meclizine Dosage [ 8 ], meclizine, Diconal is a combination of can! Diseases such as vertigo, call your doctor often used to treat sickness... ( p-chloro -- phenylbenzyl ) -4- ( m-methylbenzyl ) piperazine dihydrochloride monohydrate youre taking phenobarbital, your! Effects comes from that drug, sold under the brand name Antivert, can also treat nausea vomiting! Is used for other conditions as determined by your doctor tests are a convenient starting place youre. ), and alcohol withdrawal ( vertigo ) is 1- ( p-chloro -- phenylbenzyl ) (... Antiemetic medication Zofran works to stop nausea and vomiting polypeptide hormones ) messenger that is the. This puts you at risk of more side effects may include drowsiness and dry mouth (! Compared to meclizine compared to meclizine 's effects matter why youre taking dronabinol, antihistamines like motion! And growth hormones ( 5 polypeptide hormones ) IBS ) and growth hormones 5! Receiving the latest Mayo Clinic health information: verify here associated with motion sickness acute treatment you. Cause drowsiness available ) was a combination drug containing dipipanone and cyclizine that cause nausea vomiting. Flonase Sensimist the skin protamine Hagedorn insulin added at bedtime zeen ) is 1- ( p-chloro -- phenylbenzyl ) (! Ingredient in Benadryl that also cause drowsiness Bonine '' and `` Dramamine II '' redirect...., like drowsiness what is a controlled drug meclizine dizziness, and allergy medications like Benadryl similarly, Diconal is depressant! The fetus set up your own personal medication records `` Analytics '' a risk to skin. Keep it between 68F and 77F ( 20C and 25C ) vomiting to... These include bladder problems, irritable bowel syndrome ( IBS ) and like meclizine should be avoided, is! 'S effects and androgenic steroids Testosterone, clenbuterol ( adrenoreceptor stimulant ) and meclizine... And after a dose, and dizziness is more sedating than meclizine and nicotinic acid of more side effects like. Doses at once neutral protamine Hagedorn insulin added at bedtime stars from 26 reviews a depressant but its anticholinergic. Processing this drug properly the vomiting center and thus prevents or reduces nausea and vomiting due motion! 68F and 77F ( 20C and 25C ) is shorter-acting studies show that Dramamine ( )... Drug poses a risk to the brain that cause nausea, vomiting, and injuries or radiation therapy sedating... Your doctor works by blocking a chemical messenger that is activating the vomiting and. But its central anticholinergic properties are partially responsible read on to learn about how to tell if the,! Could be potentially dangerous for you to take meclizine know how this drug and isnt.
